Places beginning with DE in South Dakota, United States
- Deadwood
- Deadwood, City of
- Dearborn, Township of
- Deep Creek, Township of
- Deerfield
- Deevaan Villa Development
- De Grey
- De Grey, Township of
- Delaney, Township of
- Delano County (historical)
- Delapre, Township of
- Delaware, Township of
- Dell Rapids
- Dell Rapids, City of
- Dell Rapids, Township of
- Delmont
- Delmont, City of
- Dempster
- Dempster, Township of
- Denby
- Dennis
- Denver, Township of
- Derian Subdivision
- De Smet
- De Smet, City of
- De Smet, Township of
- Detmold, Township of
- Detroit (historical), Township of
- Deuel County
- Devoe
- Devoe, Township of
- Dewey
- Dewey County
- Dewey, Township of
- Dewey, Township of
- Dewey, Township of
- De Witt, Township of
- Dexter, Township of
- Dezera