Places beginning with ME in South Dakota, United States
- Meade County
- Meadow
- Meadow, Township of
- Meadow View Addition
- Meckling
- Meckling, Township of
- Medary
- Medary, Township of
- Media, Township of
- Meers, Township of
- Melcore Acres Subdivision
- Melham
- Mellette
- Mellette, City of
- Mellette County
- Mellette, Township of
- Melrose Addition
- Melrose, Township of
- Menno
- Menno, City of
- Menno (historical), Township of
- Mentor, Township of
- Mercer (historical), Township of
- Mercier, Township of
- Merritt
- Merton (historical)
- Merton, Township of
- Mess, Township of
- Metzgerville
- Meyer County (historical)